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14D2I74 - Stem cells and their role in tissue homeostasis and regenerative medicine

Course specification
Course title Stem cells and their role in tissue homeostasis and regenerative medicine
Acronym 14D2I74
Study programme DOCTORAL ACADEMIC STUDIES
Module
Type of study PhD academic studies
Lecturer (for classes)
Lecturer/Associate (for practice)
    Lecturer/Associate (for OTC)
      ESPB 4.0 Status elective
      Condition Oblik uslovljenosti
      The goal The aim of the course is that students perceive tissue homeostasis through the prism of dynamic self-renewal and regeneration of tissues and organs. The program should enable students to better understand the different pathological processes such as neoplastic processes, acute and chronic inflammation and degeneration during aging. In addition, this course is an introduction to regenerative medicine.
      The outcome Knowledge of the regenerative capacity of different tissues and the possibility to apply this knowledge to test stem cells.
      Contents
      Contents of lectures Stem cells (SC): definition, classification and origin of the different types. The differentiation of cells. Explanation of terms: Totipotent, pluripotent, multipotent and unipotent. Cloning. Embryonic and fetal SC. SC from umbilical cord blood and Wharton jelly. Hematopoietic SC. Angiogenesis. Mesenchymal SC. Osteogenesis. Chondrogenesis. Adipogenesis. SC originating from the endoderm and ectoderm. Tissues with higher and lower regenerative potential: the nervous system, muscle, endothelium, liver. Induced pluripotent SC. Cryopreservation of cells. Clinical application. Tissue engineering. Biomaterials and biocompatibility. The reaction of tissue to biomaterials.
      Contents of exercises Analysis of the research results obtained by different techniques.
      Literature
      1. Vunjak-Novaković G. i Freshney RI. Culture of Cells for Tissue Engineering. Wiley-Liss, 2006 (ISBN -13 978-0-471-62935-1) (Original title)
      2. Tatjana Božić, Pathophysiology of domestic animals, 2012 (ISBN 978-86-6021-051-9)
      3. Bongso A. i Lee EH, Stem Cells – From Bench to Bedside – World Scientific Publishing Co. Pte. Ltd, 2005 (IBN 981-256-126-9) (Original title)
      Number of hours per week during the semester/trimester/year
      Lectures Exercises OTC Study and Research Other classes
      2
      Methods of teaching Theoretical and practical classes, critical discussion.
      Knowledge score (maximum points 100)
      Pre obligations Points Final exam Points
      Activites during lectures 10 Test paper 60
      Practical lessons Oral examination
      Projects
      Colloquia 20
      Seminars 10