14S1I02 - STRUCTURE AND FUNCTION OF CELLS, TISSUES AND ORGANS IN PHYSIOLOGICAL AND PATHOPHYSIOLOGICAL CONDITIONS

Course specification
Course title		STRUCTURE AND FUNCTION OF CELLS, TISSUES AND ORGANS IN PHYSIOLOGICAL AND PATHOPHYSIOLOGICAL CONDITIONS
Acronym		14S1I02
Study programme
Module
Type of study		specialist academic studies
Lecturer (for classes)		prof. dr Natalija Fratrić prof. dr Sanja Aleksić-Kovačević prof. dr Dragan Gvozdić prof. dr Milica Kovačević-Filipović prof. dr Danijela Kirovski prof. dr Anita Radovanović prof. dr Darko Marinković prof. dr Danica Marković
Lecturer/Associate (for practice)		prof. dr Natalija Fratrić prof. dr Sanja Aleksić-Kovačević prof. dr Dragan Gvozdić prof. dr Milica Kovačević-Filipović prof. dr Danijela Kirovski prof. dr Anita Radovanović prof. dr Darko Marinković prof. dr Danica Marković
Lecturer/Associate (for OTC)
ESPB		8.0	Status	elective
Condition		Enrolled the first semester	Oblik uslovljenosti
The goal		Connecting morpho-functional characteristics of the cell and tissue types of disorders that occur in them
The outcome		The student should understand the relationship between structure and function of appropriate types of cells and tissues as well as the mechanisms of formation and type of disorder that can develop in them. You must be aware of the basic control mechanisms involved in regulating the activity of cells and tissues in normal and pathological conditions. The student should also consider the dependence of the change of the molecular to the macroscopic level in certain types of disorders in organ functions.
Contents
Contents of lectures		Morpho-functional characteristics of different types of tissue cells and intercellular interactions. Basic metabolic pathways in cells and tissues of mammals. Antioxidant cellular mechanisms. Histocompatibility complex (Major Histocompatibility Complex). Receptor system in the organism and signaling molecules. The cell cycle and its disorders. Degeneration and cell death. Inflammation and proinflammatory cytokines. Mutations and oncogenesis. Basic elements Neuroimmunomodulation. Morpho-functional changes in certain diseases of the digestive, respiratory, cardiovascular, nervous, urinary, reproductive, endocrine and hematopoetic system.
Contents of exercises		Comparative analysis of microscopic tissue samples of healthy and altered tissues and organs in various animal species. Introduction to the basic methods of determining the antioxidant status of cells. Methods for the determination of certain cytokines. Methods for the analysis of numerous hematological parameters. The basic methods of laboratory diagnostics of particular organ disorders.
Literature
McGavin, MD, Carlton, WW, Zachary, JF, Carlton W, McGavin, D: (editors) Thomson's Special Veterinary Pathology. 3rd edition. St. Louis. Mosby. 2001. (Original title) Cotran R S, Robbins S L, Kumar V: Robbins Basic Pathology, 7th edition, Saunders, Philadelphia, 2003 (Original title) Stojic V, Veterinary physiology, Naucna, Belgrade, V Edition, 2010 Tizard IR: Veterinary Immunology, 9th edition, 2012. (Original title) Eurell JA, Frappier BL:Dellmans Texbook of Veterinary Histology, 6th edition,Blackwell Publishing, 2006. (Original title)
Number of hours per week during the semester/trimester/year
Lectures	Exercises	OTC	Study and Research	Other classes
2	1	2
Methods of teaching		Theory lessons with interactive learning with the use of audiovisual methods (Power Point, films), laboratory work, independent research.
Knowledge score (maximum points 100)
Pre obligations		Points	Final exam	Points
Activites during lectures		10	Test paper	20
Practical lessons		20	Oral examination	20
Projects
Colloquia		20
Seminars		10